Licorice is a popular confectionery and flavoring agent that comes from the roots of the Glycyrrhiza glabra plant. It has been used for centuries in traditional medicine to treat a variety of ailments, including sore throats, digestive issues, and respiratory problems. However, recent studies have suggested that licorice may have negative effects on blood pressure.
The active compound in licorice that is believed to impact blood pressure is glycyrrhizin, a sweet-tasting compound that also has mineralocorticoid properties. It has been found to inhibit the enzyme 11β-hydroxysteroid dehydrogenase type 2, which normally inactivates cortisol. When this enzyme is inhibited, cortisol levels in the body can rise, leading to increased sodium retention and potassium loss. This can result in fluid retention and increased blood pressure.
Several studies have linked the consumption of licorice with hypertension. For example, a study published in the American Journal of Hypertension found that consuming as little as 100 grams of licorice per week could lead to a significant increase in blood pressure. Another study in the journal Food and Chemical Toxicology found that glycyrrhizin could affect the renin-angiotensin-aldosterone system, which plays a key role in regulating blood pressure.
Despite these findings, it is important to note that not all studies have shown a clear link between licorice consumption and hypertension. Some studies have suggested that the effects of licorice on blood pressure may vary depending on the individual and the amount consumed. Additionally, the method of consumption (e.g. as a candy, tea, or supplement) may also impact the potential effects on blood pressure.
To reduce the risk of hypertension from licorice consumption, it is recommended to limit intake of licorice products and opt for deglycyrrhizinated licorice (DGL) supplements, which have had the glycyrrhizin removed. DGL is commonly used to treat stomach ulcers and other gastrointestinal issues without the risk of increasing blood pressure.
In conclusion, while there is evidence to suggest that licorice may impact blood pressure, the link between licorice consumption and hypertension is not yet fully understood. It is important to consume licorice in moderation and consult with a healthcare provider if you have concerns about its potential effects on your blood pressure. Additionally, choosing DGL supplements may be a safer alternative for individuals looking to avoid the potential negative effects of licorice on blood pressure.